Membrane-cytoskeleton mechanical feedback mediated by myosin-I controls phagocytic efficiency
S. R. Barger, N. S. Reilly, M. S. Shutova, Q. Li, P. Maiuri, M. S. Mooseker, R. A. Flavell, T. Svitkina, P. W. Oakes, M. Krendel, N. Gauthier
The paper shows that myosin 1e and 1f are required for efficient phagocytosis by regulating adhesion turnover and actin dynamics during phagocytic cup closure.
bioRxiv · Oct 2, 2018Cell Biology