Author

M. Saichi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

E. Amblard· 2 shared F. Noel· 2 shared S. Korniotis· 2 shared V. Soumelis· 2 shared A. Durand· 1 shared A. Trouchet· 1 shared A. Viguier· 1 shared C. Hoffmann· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersImmunology

E. Amblard

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Luminal progenitors undergo partial epithelial-to-mesenchymal transition at the onset of basal-like breast tumorigenesis

C. Landragin, M. Saichi, P. Prompsy, A. Durand, J. Mesple, A. Trouchet, M. Faraldo, H. Salmon, C. Vallot

The paper identifies a pre-tumoral state in luminal progenitor cells during basal-like breast tumorigenesis, characterized by partial epithelial-to-mesenchymal transition and epigenomic changes.

bioRxiv · Jun 8, 2022 · PreprintCancer Biology

GM-CSF-activated human dendritic cells promote type1 T follicular helper cells (Tfh1) polarization in a CD40-dependent manner

S. Korniotis, M. Saichi, C. Trichot, C. Hoffmann, E. Amblard, A. Viguier, S. Grondin, F. Noel, H. Mattoo, V. Soumelis

This study shows GM-CSF-activated human dendritic cells drive Tfh1 differentiation via CD40-dependent mechanisms, with implications for infections like tuberculosis and COVID-19.

bioRxiv · Apr 28, 2022 · PreprintImmunology

Single cell RNA sequencing of blood antigen-presenting cells in severe Covid-19 reveals multi-process defects in antiviral immunity

M. Saichi, M. Z. Ladjemi, S. Korniotis, C. Rousseau, Z. Ait-Hamou, L. Massenet, E. Amblard, F. Noel, Y. Marie, D. Bouteiller, J. Medvedovic, F. Pene, V. Soumelis

This study uses single-cell RNA sequencing to analyze blood antigen-presenting cells in severe COVID-19 patients, identifying defects in antiviral immunity.

bioRxiv · Jul 20, 2020Immunology