Author

M. Saitou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Organism:chicken / avian· 1

Frequent Co-Authors

G. E. Atilla-Gokcumen· 2 shared O. Gokcumen· 2 shared A. J. Pradhan· 1 shared A. Millner· 1 shared A. Takaori-Kondo· 1 shared C. Diblasi· 1 shared C. Iwatani· 1 shared C. Lee· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersEvolutionary Biology

G. E. Atilla-Gokcumen

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Atlas of Cynomolgus Macaque Hematopoiesis

S. Oshima, R. Sinha, K. Takeuchi, K. Mizuta, T. Nakamura, R. Ito, I. Kawamoto, C. Iwatani, M. Nakaya, H. Tsuchiya, S. Bhagat, T. Tsukiyama, A. Takaori-Kondo, M. Saitou, Y. Murakawa, R. Yamamoto

The paper develops a single-cell transcriptomic map of cynomolgus macaque hematopoietic stem cells and progenitors, revealing molecular differences from humans and a direct differentiation pathway to megakaryocyte lineages.

bioRxiv · Apr 22, 2024 · PreprintCell Biology

Functional and regulatory diversification of period genes responsible for circadian rhythm in vertebrates

J. S. KWAK, M. A. Leon-Tapia, C. Diblasi, D. Manousi, L. Gronvold, G. K. Sandvik, M. Saitou

This study investigates the evolutionary diversification of Period genes across vertebrates, finding rapid evolution and sub-functionalization, especially in protein-binding regions critical for circadian regulation.

bioRxiv · Mar 9, 2023 · PreprintEvolutionary Biology

Sex-specific phenotypic effects and evolutionary history of an ancient polymorphic deletion of the human growth hormone receptor

M. Saitou, S. Resendez, A. J. Pradhan, F. Wu, N. C. Lie, N. J. Hall, Q. Zhu, L. Reinholdt, Y. Satta, S. Nakagome, N. A. Hanchard, G. Churchill, C. Lee, G. E. Atilla-Gokcumen, X. Mu, O. Gokcumen

This study investigates the evolutionary history and phenotypic effects of the GHRd3 deletion, finding sex- and environment-dependent impacts on growth and metabolism.

bioRxiv · Mar 1, 2021Evolutionary Biology

An evolutionary transcriptomics approach links CD36 to membrane remodeling in replicative senescence

M. Saitou, D. Lizardo, R. Taskent, A. Millner, G. E. Atilla-Gokcumen, O. Gokcumen

This study identifies CD36 as a key gene upregulated in senescent cells, linking it to membrane remodeling through lipid metabolism and senescence-like phenotypes.

bioRxiv · Apr 3, 2018Cell Biology