Author

S. Oshima

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 1 Organism:chicken / avian· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Nakagawa· 1 shared A. Takaori-Kondo· 1 shared B. S. Moriarity· 1 shared C. Iwatani· 1 shared C. Ono· 1 shared D. Largaespada· 1 shared H. Arase· 1 shared H. Tsuchiya· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperMicrobiology

A. Nakagawa

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Atlas of Cynomolgus Macaque Hematopoiesis

S. Oshima, R. Sinha, K. Takeuchi, K. Mizuta, T. Nakamura, R. Ito, I. Kawamoto, C. Iwatani, M. Nakaya, H. Tsuchiya, S. Bhagat, T. Tsukiyama, A. Takaori-Kondo, M. Saitou, Y. Murakawa, R. Yamamoto

The paper develops a single-cell transcriptomic map of cynomolgus macaque hematopoietic stem cells and progenitors, revealing molecular differences from humans and a direct differentiation pathway to megakaryocyte lineages.

bioRxiv · Apr 22, 2024 · PreprintCell Biology

SARS-CoV-2 ORF8 is a viral cytokine regulating immune responses

M. Kohyama, T. Suzuki, W. Nakai, C. Ono, S. Matsuoka, K. Iwatani, Y. Liu, Y. Sakai, A. Nakagawa, K. Tomii, K. Ohmura, M. Okada, Y. Matsuura, S. Oshima, Y. Maeda, , H. Arase

This study shows that SARS-CoV-2 ORF8 protein acts as a cytokine that promotes lung inflammation and immune dysregulation in COVID-19, suggesting it as a potential therapeutic target.

bioRxiv · Aug 1, 2022Microbiology

Indirect CRISPR screening with photoconversion revealed key factors of drug resistance with cell-cell interactions

K. Sugita, I. Onishi, R. Nakayama, S. Ishibashi, M. Ikeda, M. Inoue, R. Narita, S. Oshima, K. Shimizu, S. Saito, S. Sato, B. S. Moriarity, K. Yamamoto, D. Largaespada, M. Kitagawa, M. Kurata

This study uses indirect CRISPR screening with photoconversion to identify key factors of drug resistance mediated by cell-cell interactions, finding genes that reduce cancer cell apoptosis when knocked out in supporting cells.

bioRxiv · Jul 15, 2022Cancer Biology