Multifocal two-photon excitation fluorescence microscopy reveals hop diffusion of H-Ras membrane anchors in epidermal cells of zebrafish embryos
R. J. Gora, R. C. Vlieg, S. Jonkers, J. van Noort, M. Schaaf
bioRxiv · Oct 25, 2022 · PreprintBiophysics
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R. J. Gora, R. C. Vlieg, S. Jonkers, J. van Noort, M. Schaaf
bioRxiv · Oct 25, 2022 · PreprintBiophysics
R. J. Gora, B. de Jong, P. van Hage, M. A. Rhiemus, F. van Steenis, J. van Noort, T. Schmidt, M. Schaaf
The paper uses single-molecule microscopy to analyze H-Ras protein dynamics in zebrafish embryos, revealing cellular heterogeneity in diffusion rates.
bioRxiv · Jun 21, 2021Biophysics
Y. Xie, A. H. Meijer, M. Schaaf
This study shows glucocorticoids reduce macrophage phagocytosis, increasing bacterial burden in a zebrafish tuberculosis model, which may explain increased susceptibility to tuberculosis in humans.
bioRxiv · Jun 19, 2020 · PreprintImmunology
R. van den Bos, S. Cromwijk, K. Tschigg, J. Althuizen, J. Zethof, R. Whelan, G. Flik, M. Schaaf
This study shows that early-life cortisol exposure in zebrafish larvae enhances immune responses and survival to LPS challenge via the glucocorticoid receptor.
bioRxiv · Dec 11, 2019Immunology