Author

M. Schlame

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Bartelt· 1 shared B. P. Pedersen· 1 shared C. Larsen· 1 shared D. L. Stokes· 1 shared G. S. Hotamisligil· 1 shared M. Balazova· 1 shared M. Chakkour· 1 shared M. D. Brand· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperBiochemistry

A. Bartelt

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction and leads to increased glucose uptake in tafazzin-deficient cells

Z. Liang, T. Ralph-Epps, M. W. Schmidtke, P. Lazcano, S. W. Denis, M. Balazova, M. Chakkour, S. Hazime, M. Ren, M. Schlame, R. Houtkooper, M. Greenberg

This study identifies the upregulation of the AMPK-FOXO1-PDK4 pathway as the mechanism causing reduced PDH activity and increased glucose uptake in tafazzin-deficient cells.

bioRxiv · Feb 3, 2024 · PreprintCell Biology

Structural basis for Potassium transport by KdpFABC

M. E. Sweet, C. Larsen, X. Zhang, M. Schlame, B. P. Pedersen, D. L. Stokes

This study determines the structural basis of K+ transport by KdpFABC using cryo-EM, revealing a pathway and mechanism involving conformational changes in KdpB and a static KdpA.

bioRxiv · Jan 9, 2021 · PreprintBiophysics

An unexpected lack of difference in superoxide/H2O2 production rates in isolated heart and skeletal muscle mitochondria from a mouse model of Barth Syndrome

R. L. S. Goncalves, M. Schlame, A. Bartelt, M. D. Brand, G. S. Hotamisligil

The study measures superoxide/H2O2 production in mitochondria from BTHS mice and finds no overall increase, except for a specific site in skeletal muscle.

bioRxiv · May 7, 2020 · PreprintBiochemistry