Phenotypic profile of Mycobacterium tuberculosis-specific CD4 T cell responses in HIV-positive patients who develop Tuberculosis-associated Immune Reconstitution Inflammatory Syndrome
M. R. Moseki, D. Barber, E. Du Bruyn, M. Shey, H. Van der Plas, R. J. Wilkinson, G. Meintjes, C. Riou
The paper examines Mtb-specific CD4 T cell responses in HIV-positive patients with TB-IRIS, finding higher IFN-gamma+CD4 T cell activation and Granzyme B expression at IRIS onset.
bioRxiv · Jul 20, 2022 · PreprintImmunology