Author

W. Hanekom

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:flow cytometry· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Research Focus:clustering· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Gela· 2 shared A. Sigal· 2 shared COMMIT-KZN Team· 2 shared E. Nemes· 2 shared F. Karim· 2 shared K. Khan· 2 shared M. Bernstein· 2 shared M. Hatherill· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

A. Gela

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

HIV skews the SARS-CoV-2 B cell response toward an extrafollicular maturation pathway

R. Krause, COMMIT-KZN Team, J. Snyman, S.-H. Hwa, D. Muema, F. Karim, Y. Ganga, A. Ngoepe, Y. Zungu, I. Gazy, M. Bernstein, K. Khan, M. Mazibuko, N. Mthabela, D. Ramjit, , A. Leslie

This study shows that HIV infection shifts the SARS-CoV-2 B cell response toward an extrafollicular pathway, leading to lower affinity antibodies and reduced vaccine efficacy in people living with HIV.

bioRxiv · Jun 14, 2022Immunology

SARS-CoV-2 cell-to-cell spread occurs rapidly and is insensitive to antibody neutralization

L. Jackson, H. Rodel, S.-H. Hwa, S. Cele, Y. Ganga, H. Tegally, M. Bernstein, J. Giandhari, COMMIT-KZN Team, B. I. Gosnell, K. Khan, W. Hanekom, F. Karim, T. de Oliveira, M.-Y. S. Moosa, A. Sigal

This study shows SARS-CoV-2 spreads rapidly between cells via fusion and is resistant to antibody neutralization, unlike cell-free virus.

bioRxiv · Jun 1, 2021 · PreprintMicrobiology

Effects of BCG vaccination on donor unrestricted T cells in humans

A. Gela, M. Murphy, K. Hadley, W. Hanekom, H. Boom, J. Johnson, D. Hoft, S. Joosten, T. Ottenhoff, S. Suliman, B. Moody, D. Lewinsohn, M. Hatherill, C. Seshadri, E. Nemes, T. Scriba

This study examines the effects of BCG vaccination on donor unrestricted T (DURT) cells in humans, finding increased frequencies of certain T cell subsets in infants but no changes in others.

bioRxiv · Apr 29, 2021 · PreprintImmunology

Postnatal expansion, maturation and functionality of MR1 T cells in humans

G. M. Swarbrick, A. Gela, M. E. Cansler, M. D. Null, R. B. Duncan, E. Nemes, M. Shey, M. Nsereko, H. Mayanja-Kizza, S. Kiguli, J. Koh, W. Hanekom, M. Hatherill, C. Lancioni, D. M. Lewinsohn, , D. A. Lewinsohn

This study examines the postnatal development of MR1-restricted T cells in humans, showing their expansion, maturation, and functional maturation in response to environmental exposure and tuberculosis infection.

bioRxiv · Dec 20, 2019 · PreprintImmunology