Author

G. M. Swarbrick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

D. A. Lewinsohn· 3 shared D. M. Lewinsohn· 3 shared E. J. Adams· 2 shared M. Cansler· 2 shared M. Null· 2 shared N. A. Ladd· 2 shared W. H. Hildebrand· 2 shared A. Gela· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersImmunology

D. A. Lewinsohn

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3 papers

Recent·Most cited

Delivery of loaded MR1 Monomer Results in Efficient Ligand Exchange to Host MR1 and Subsequent MR1T cell activation

C. A. Kulicke, G. M. Swarbrick, N. A. Ladd, M. Cansler, M. Null, A. Worley, C. Lemon, T. Ahmed, J. Bennett, T. N. Lust, C. M. Heisler, M. E. Huber, J. R. Krawic, L. M. Ankley, S. K. McBride, , M. J. Harriff

The paper demonstrates that delivering MR1 monomers loaded with 5-OP-RU enables ligand exchange to host MR1, leading to MR1T cell activation.

bioRxiv · Jul 11, 2022Immunology

Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells

H. Jin, N. A. Ladd, A. M. Peev, G. M. Swarbrick, M. Cansler, M. Null, C. T. Boughter, C. McMurtrey, A. Nilsen, K. M. Dobos, W. H. Hildebrand, D. A. Lewinsohn, E. J. Adams, D. M. Lewinsohn, M. Harriff

This study modifies MR1 ligands to assess their impact on MR1-restricted T cell activation, revealing variable IFN-gamma responses and structural dynamics influencing recognition.

bioRxiv · May 11, 2022Immunology

Postnatal expansion, maturation and functionality of MR1 T cells in humans

G. M. Swarbrick, A. Gela, M. E. Cansler, M. D. Null, R. B. Duncan, E. Nemes, M. Shey, M. Nsereko, H. Mayanja-Kizza, S. Kiguli, J. Koh, W. Hanekom, M. Hatherill, C. Lancioni, D. M. Lewinsohn, , D. A. Lewinsohn

This study examines the postnatal development of MR1-restricted T cells in humans, showing their expansion, maturation, and functional maturation in response to environmental exposure and tuberculosis infection.

bioRxiv · Dec 20, 2019 · PreprintImmunology