Author

E. Du Bruyn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:flow cytometry· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

C. Riou· 4 shared R. J. Wilkinson· 4 shared K. D. Mayer-Barber· 3 shared A. Sher· 2 shared D. Barber· 2 shared D. L. Barber· 2 shared M. Ntsekhe· 2 shared S. Ruzive· 2 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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4 shared papersImmunology

C. Riou

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4 papers

Recent·Most cited

Blood and site of disease inflammatory profiles differ in HIV-1-infected pericardial tuberculosis patients

H. Mutavhatsindi, E. Du Bruyn, S. Ruzive, P. Howlett, A. Sher, K. D. Mayer-Barber, D. L. Barber, M. Ntsekhe, R. J. Wilkinson, C. Riou

This study compares inflammatory profiles in blood and pericardial fluid of HIV-1-infected individuals with latent TB, PTB, and PCTB, finding site-specific elevation of analytes and HLA-DR as a better TB diagnostic marker.

bioRxiv · Oct 21, 2022 · PreprintImmunology

Phenotypic profile of Mycobacterium tuberculosis-specific CD4 T cell responses in HIV-positive patients who develop Tuberculosis-associated Immune Reconstitution Inflammatory Syndrome

M. R. Moseki, D. Barber, E. Du Bruyn, M. Shey, H. Van der Plas, R. J. Wilkinson, G. Meintjes, C. Riou

The paper examines Mtb-specific CD4 T cell responses in HIV-positive patients with TB-IRIS, finding higher IFN-gamma+CD4 T cell activation and Granzyme B expression at IRIS onset.

bioRxiv · Jul 20, 2022 · PreprintImmunology

Profile of Mycobacterium tuberculosis-specific CD4 T cells at the site of disease and blood in pericardial tuberculosis

E. Du Bruyn, S. Ruzive, P. J. Howlett, A. J. Jacobs, C. S. Lindestam Arlehamn, A. Sette, A. Sher, K. D. Mayer-Barber, D. Barber, B. Mayosi, M. Ntsekhe, R. J. Wilkinson, C. Riou

This study compares Mtb-specific CD4 T cell profiles in pericardial fluid and blood from PCTB patients, finding distinct phenotypes in PCF with no difference in cytokine production.

bioRxiv · May 12, 2022 · PreprintImmunology

Eosinophils are an integral component of the pulmonary granulocyte response in Tuberculosis and promote host resistance in mice

A. C. Bohrer, E. Castro, Z. Hu, A. T. L. Queiroz, C. E. Tocheny, M. Assmann, S. Sakai, C. Nelson, P. J. Baker, H. Ma, L. Wang, W. Zilu, E. du Bruyn, C. Riou, K. D. Kauffman, , K. D. Mayer-Barber

This study shows eosinophils are recruited to tuberculosis-infected lung tissue in mice and contribute to host resistance against Mtb infection.

bioRxiv · May 29, 2021Immunology