Author

M. Sigvardsson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

B. A. Williams· 1 shared B. L. Kee· 1 shared C. Frank· 1 shared E. T. Bartom· 1 shared E. V. Rothenberg· 1 shared H. Hosokawa· 1 shared J. Ungerback· 1 shared M. Greger· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

B. A. Williams

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2 papers

Recent·Most cited

TGF-β promotes the postselection thymic development and peripheral function of interferon-γ-producing iNKT cells

R. C. Morgan, C. Frank, M. Greger, M. Sigvardsson, E. T. Bartom, B. L. Kee

This study shows TGF-β is required for thymic iNKT1 cell development and adhesion receptor expression, but not for liver iNKT1 cell function.

bioRxiv · Oct 23, 2022 · PreprintImmunology

Pioneering, chromatin remodeling, and epigenetic constraint in early T-cell gene regulation by PU.1

J. Ungerback, H. Hosokawa, X. Wang, T. Strid, B. A. Williams, M. Sigvardsson, E. V. Rothenberg

This study investigates PU.1's pioneering activity in early T-cell development, showing its ability to bind and open closed chromatin sites despite lacking collaborators, and its role in regulating gene accessibility and transcription.

bioRxiv · May 25, 2018Immunology