Author

B. L. Kee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

E. T. Bartom· 3 shared C. Frank· 2 shared C. Saygin· 1 shared E. Hegermiller· 1 shared G. Parriott· 1 shared H.-H. Xue· 1 shared M. Greger· 1 shared M. M. Le Beau· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCancer Biology

E. T. Bartom

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Loss of thymocyte competition underlies the tumor suppressive functions of the E2a transcription factor in T lymphocyte acute lymphoblastic leukemia.

G. Parriott, E. Hegermiller, R. E. Morman, C. Frank, C. Saygin, W. Stock, E. T. Bartom, B. L. Kee

This study shows that E2a suppresses T-ALL by promoting T cell development and inter-thymocyte competition, preventing leukemogenesis.

bioRxiv · Apr 23, 2023 · PreprintCancer Biology

TGF-β promotes the postselection thymic development and peripheral function of interferon-γ-producing iNKT cells

R. C. Morgan, C. Frank, M. Greger, M. Sigvardsson, E. T. Bartom, B. L. Kee

This study shows TGF-β is required for thymic iNKT1 cell development and adhesion receptor expression, but not for liver iNKT1 cell function.

bioRxiv · Oct 23, 2022 · PreprintImmunology

Oncogenic and Tumor Suppressor Functions for Lymphoid Enhancer Factor 1 in a Murine Model of T Acute Lymphoblastic Leukemia

T. Carr, S. McGregor, S. Dias, M. Verykokakis, M. M. Le Beau, H.-H. Xue, E. T. Bartom, B. L. Kee

This study shows that the timing of Lef1 mutations in a murine T-ALL model affects its role as a tumor suppressor or oncogene, highlighting the importance of mutational order in leukemogenesis.

bioRxiv · Nov 8, 2021 · PreprintCancer Biology