Author

M. Spiess

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 4 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Organism:human· 2 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. Prescianotto-Baschong· 3 shared A. Spang· 1 shared A. Wiesyk· 1 shared C. Forsyth· 1 shared D. Hoepfner· 1 shared D. P. Buser· 1 shared E. Demirci· 1 shared E. Park· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersCell Biology

C. Prescianotto-Baschong

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

A common mechanism of Sec61 translocon inhibition by small molecules

S. Itskanov, L. Wang, T. Junne, R. Sherriff, L. Xiao, N. Blanchard, W. Q. Shi, C. Forsyth, D. Hoepfner, M. Spiess, E. Park

This study identifies a common binding site for diverse Sec61 inhibitors and shows how they stabilize the plug domain to block protein translocation.

bioRxiv · Aug 11, 2022Biochemistry

The small GTPase Arf1 regulates ATP synthesis and mitochondria homeostasis by modulating fatty acid metabolism

L. Enkler, M. V. Pennauer, V. Szentgyörgyi, C. Prescianotto-Baschong, I. Riezman, A. Wiesyk, R. Kucharczyk, M. Spiess, H. Riezman, A. Spang

This study shows that Arf1 regulates fatty acid metabolism, affecting mitochondrial homeostasis and ATP synthesis in yeast.

bioRxiv · Jan 26, 2022 · PreprintCell Biology

Small disulfide loops in peptide hormones mediate self-aggregation and secretory granule sorting

J. R. Reck, N. Beuret, E. Demirci, C. Prescianotto-Baschong, M. Spiess

The paper shows small disulfide loops in peptide hormones drive self-aggregation and secretory granule sorting through ER and TGN studies.

bioRxiv · Aug 20, 2021Cell Biology

Shared and specific functions of Arfs 1-5 at the Golgi revealed by systematic knockouts

M. Pennauer, K. Buczak, C. Prescianotto-Baschong, M. Spiess

This study uses CRISPR/Cas9 to knockout Arfs 1-5 in human cells, revealing their specific and shared functions in Golgi structure and membrane trafficking.

bioRxiv · Apr 19, 2021Cell Biology

Rabaptin5 targets autophagy to damaged early endosomes and Salmonella containing vacuoles by interaction with FIP200 and ATG16L1

V. Millarte, S. Schlienger, S. Kälin, M. Spiess

This study identifies Rabaptin5's role in autophagy targeting damaged early endosomes and Salmonella-containing vacuoles through interactions with FIP200 and ATG16L1.

bioRxiv · Sep 1, 2020Cell Biology

Retrograde transport of mannose-6-phosphate receptor depends on several sorting machineries as analyzed by sulfatable nanobodies

D. P. Buser, M. Spiess

This study uses sulfatable nanobodies to analyze retrograde transport of CDMPR, showing that AP-1, retromer, epsinR, and Rab9 are required, while GGA proteins inhibit transport.

bioRxiv · Dec 21, 2019 · PreprintCell Biology