High-throughput Screening with Pluripotent Stem Cells Identifies CUDC-907 as an Effective Compound for Restoring the Proinflammatory Phenotype of Nakajo-Nishimura Syndrome
N. Kase, M. Terashima, A. Ohta, A. Niwa, F. Honda-Ozaki, Y. Kawasaki, T. Nakahata, N. Kanazawa, M. Saito
This study uses a pluripotent stem cell-derived model of Nakajo-Nishimura syndrome to identify CUDC-907 as a compound that reduces inflammatory chemokine overproduction.
bioRxiv · Jun 1, 2020Immunology