Large-scale genetic screens identify BET-1 as a cytoskeleton regulator promoting actin health and lifespan.
G. Garcia, R. Bar-Ziv, N. Dutta, D. Moaddeli, M. Averbukh, T. C. Torres, A. Alcala, C. K. Tsui, E. A. Moehle, O. Shalem, M. Thorwald, R. Higuchi-Sanabria
The paper identifies BET-1 as a regulator of actin health and lifespan through genetic screens in human fibroblasts and C. elegans.
bioRxiv · Jun 22, 2022 · PreprintCell Biology