Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle
D. J. Ham, A. Boersch, K. Chojnowska, S. Lin, A. B. Leuchtmann, A. S. Ham, M. Thuerkauf, J. Delezie, R. Furrer, D. Burri, M. Sinnreich, C. Handschin, L. A. Tintignac, M. Zavolan, N. Mittal, M. A. Ruegg
This study shows that calorie restriction and rapamycin have distinct and additive effects on aging skeletal muscle gene expression and function in mice.
bioRxiv · May 28, 2021Physiology