Author

A. Boersch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Assay:flow cytometry· 2 Assay:proteomics· 2

Frequent Co-Authors

M. Zavolan· 2 shared A. B. Leuchtmann· 1 shared A. Barbero· 1 shared A. Correia· 1 shared A. Mainardi· 1 shared A. S. Ham· 1 shared A. Schmidt· 1 shared A. Syed· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersPhysiology

M. Zavolan

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Modelling Osteoarthritis pathogenesis through Mechanical Loading in an Osteochondral Unit-on-Chip

A. Mainardi, A. Boersch, P. Occhetta, R. Ivanek, M. Ehrbar, L. A. Krattiger, P. Oertle, M. Loparic, I. Martin, M. Rasponi, A. Barbero

This study develops an OCU-on-chip system to model OA pathogenesis under mechanical loading, identifying novel metabolic drivers and molecular targets for OA therapies.

bioRxiv · Aug 29, 2023Bioengineering

Engagement of sialylated glycans with Siglec receptors on myeloid suppressor cells inhibit anti-cancer immunity via CCL2

R. Wieboldt, E. Carlini, L. Chia-wei, A. Boersch, A. Zingg, D. Lardinois, P. Herzig, L. Don, A. Zippelius, H. Laeubli, N. Rodrigues Mantuano

This study shows that sialylated glycans on myeloid suppressor cells interact with Siglec receptors to suppress anti-cancer immunity through CCL2-mediated mechanisms.

bioRxiv · Jun 29, 2023 · PreprintImmunology

Combined multidimensional single-cell protein and RNA profiling dissects the cellular and functional heterogeneity of thymic epithelial cells

F. Klein, C. Veiga-Villauriz, A. Boersch, S. Maio, S. Palmer, S. Zuklys, I. Calvo-Asensio, L. Musette, M. E. Deadman, F. Dhalla, A. White, B. Lucas, G. Anderson, G. A. Hollaender

The paper uses combined single-cell protein and RNA profiling to identify and characterize novel subpopulations of thymic epithelial cells and their functional roles.

bioRxiv · Sep 14, 2022Immunology

Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle

D. J. Ham, A. Boersch, K. Chojnowska, S. Lin, A. B. Leuchtmann, A. S. Ham, M. Thuerkauf, J. Delezie, R. Furrer, D. Burri, M. Sinnreich, C. Handschin, L. A. Tintignac, M. Zavolan, N. Mittal, M. A. Ruegg

This study shows that calorie restriction and rapamycin have distinct and additive effects on aging skeletal muscle gene expression and function in mice.

bioRxiv · May 28, 2021Physiology

AGO1x prevents dsRNA-induced interferon signaling to promote breast cancer cell proliferation

S. Ghosh, J. Guimaraes, M. Lanzafame, A. Schmidt, A. Syed, B. Dimitriades, A. Boersch, S. Ghosh, A. Correia, J. Danner, G. Meister, L. Terracciano, S. Piscuoglio, M. Zavolan

This study identifies AGO1x, a nuclear Argonaute isoform, as a suppressor of dsRNA-induced interferon signaling that promotes breast cancer cell proliferation.

bioRxiv · Apr 10, 2019Cell Biology