Author

M. Zavolan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Biophysics· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

N. Mittal· 3 shared A. Boersch· 2 shared A. Schmidt· 2 shared D. J. Ham· 2 shared K. Chojnowska· 2 shared L. A. Tintignac· 2 shared M. A. Ruegg· 2 shared S. Lin· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersPhysiology

N. Mittal

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

T helper cells exhibit a dynamic and reversible 3'UTR landscape.

D. Seyres, O. Gorka, R. Schmidt, R. Marone, M. Zavolan, L. T. Jeker

The paper examines 3'UTR dynamics in T helper cells, finding that alternative polyadenylation (APA) events are transient and do not strongly correlate with differential gene expression.

bioRxiv · Jan 19, 2023Immunology

Dual roles of mTORC1-dependent activation of the ubiquitin-proteasome system in muscle proteostasis

M. S. Kaiser, G. Milan, S. Lin, F. Oliveri, K. Chojnowska, L. A. Tintignac, N. Mittal, C. E. Zimmerli, D. J. Glass, M. Zavolan, D. J. Ham, M. A. Ruegg

The paper reveals that mTORC1 promotes muscle atrophy by enhancing the ubiquitin-proteasome system through dual mechanisms, while also showing that proteome integrity depends on ubiquitination.

bioRxiv · Nov 16, 2021Physiology

Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle

D. J. Ham, A. Boersch, K. Chojnowska, S. Lin, A. B. Leuchtmann, A. S. Ham, M. Thuerkauf, J. Delezie, R. Furrer, D. Burri, M. Sinnreich, C. Handschin, L. A. Tintignac, M. Zavolan, N. Mittal, M. A. Ruegg

This study shows that calorie restriction and rapamycin have distinct and additive effects on aging skeletal muscle gene expression and function in mice.

bioRxiv · May 28, 2021Physiology

AGO1x prevents dsRNA-induced interferon signaling to promote breast cancer cell proliferation

S. Ghosh, J. Guimaraes, M. Lanzafame, A. Schmidt, A. Syed, B. Dimitriades, A. Boersch, S. Ghosh, A. Correia, J. Danner, G. Meister, L. Terracciano, S. Piscuoglio, M. Zavolan

This study identifies AGO1x, a nuclear Argonaute isoform, as a suppressor of dsRNA-induced interferon signaling that promotes breast cancer cell proliferation.

bioRxiv · Apr 10, 2019Cell Biology

Protein synthesis rates and ribosome occupancies reveal determinants of translation elongation rates

A. Riba, N. Di Nanni, N. Mittal, E. Arhne, A. Schmidt, M. Zavolan

The paper infers translation initiation and elongation rates for yeast ORFs using ribosome footprinting and protein synthesis data, finding amino acid composition and codon/tRNA adaptation equally influence elongation rates.

bioRxiv · Nov 8, 2018Biophysics