A computational model predicts sex-specific responses to calcium channel blockers in mammalian mesenteric vascular smooth muscle
G. Hernandez Hernandez, S. C. O'Dwyer, C. Matsumoto, M. Tieu, Z. Fong, P.-C. Yang, T. J. Lewis, L. F. Santana, C. E. Clancy
The paper develops a computational model to predict sex-specific responses to calcium channel blockers in arterial smooth muscle, revealing differences in ion channel regulation between male and female myocytes.
bioRxiv · Jun 24, 2023Physiology