Author

P. J. Dunn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Comba· 2 shared A. E. Argento· 2 shared M. G. Castro· 2 shared P. R. Lowenstein· 2 shared A. Kahana· 1 shared C. Abel· 1 shared C. E. Brown· 1 shared C. G. Kleer· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersCancer Biology

A. Comba

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Author profile →

2 papers

Recent·Most cited

Spatiotemporal analysis of glioma heterogeneity reveals Col1A1 as an actionable 1 target to disrupt tumor mesenchymal differentiation, invasion and malignancy

A. Comba, S. M. Faisal, P. J. Dunn, A. E. Argento, T. C. Hollon, W. Al-Holou, M. L. Varela, D. B. Zamler, G. L. Quass, P. F. Apostolides, C. Abel, C. E. Brown, P. E. Kish, A. Kahana, C. G. Kleer, , P. R. Lowenstein

The paper identifies COL1A1 as a key driver of glioma mesenchymal differentiation and invasion, showing its inhibition disrupts tumor structure and improves survival.

bioRxiv · Dec 1, 2020 · PreprintCancer Biology

FYN tyrosine kinase, a downstream target of receptor tyrosine kinases, modulates anti-glioma immune responses

A. Comba, P. J. Dunn, A. E. Argento, P. Kadiyala, M. Ventosa, P. Patel, D. Zamler, F. J. Nunez, L. Zhao, M. G. Castro, P. R. Lowenstein

This study shows that FYN tyrosine kinase in glioma cells suppresses anti-glioma immune responses, and its inhibition reduces tumor growth and improves survival in immune-competent models.

bioRxiv · Dec 17, 2019Cancer Biology