Author

M. von Mehren

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

D. Sharipova· 2 shared K. Devarajan· 2 shared L. Rink· 2 shared M. G. Belinsky· 2 shared M. Kozinova· 2 shared S. Litwin· 2 shared S. Ye· 2 shared A. R. Campos· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersCancer Biology

D. Sharipova

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2 papers

Recent·Most cited

Cancer BiologybioRxivApr 13, 2021

Combined Inhibition of AKT and KIT Restores Expression of Programmed Cell Death 4 (PDCD4) in Gastrointestinal Stromal Tumor

M. Kozinova, S. Joshi, S. Ye…·L. Rink

This study shows that combining AKT and KIT inhibitors restores PDCD4 expression in GIST cells, leading to cell death, but the combination is less effective in IM-resistant models.

DOI 10.3390/cancers13153699

humanproteomics

𝕏 PostBluesky

Cancer BiologybioRxivJun 7, 2020

Identification of Wee1 as Target in Combination with Avapritinib for the Treatment of Gastrointestinal Stromal Tumors

S. Ye, D. Sharipova, M. Kozinova…·L. Rink

This study identifies Wee1 as a therapeutic target in combination with avapritinib for treating gastrointestinal stromal tumors (GIST) by analyzing kinome profiles and conducting functional assays.

DOI 10.1172/jci.insight.143474

humanproteomics

𝕏 PostBluesky