A nesprin-4/kinesin-1 cargo model for nuclear positioning in cochlear outer hair cells
S. Taiber, O. Gozlan, R. Cohen, L. R. Andrade, E. F. Gregory, D. A. Starr, Y. Moran, R. Hipp, M. W. Kelley, U. Manor, D. Sprinzak, K. B. Avraham
This study identifies a conserved 4-amino-acid motif in nesprin-4 that mediates its interaction with kinesin-1, essential for nuclear positioning in outer hair cells and hearing.
bioRxiv · Oct 10, 2021Cell Biology