Author

D. Sprinzak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Organism:C. elegans· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

O. Gozlan· 2 shared A. M. Vollmar· 1 shared D. A. Starr· 1 shared E. F. Gregory· 1 shared H. Jiang· 1 shared H. Zhou· 1 shared J. C. Aster· 1 shared K. B. Avraham· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

O. Gozlan

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Structural Requirements for Activity of Mind bomb1 in Notch Signaling

R. Cao, O. Gozlan, L. Tveriakhina, H. Zhou, H. Jiang, P. A. Cole, J. C. Aster, D. Sprinzak, S. C. Blacklow

This study identifies the structural requirements of MIB1 for ubiquitin transfer in Notch signaling, showing that RING3 is essential for catalytic activity and dimerization.

bioRxiv · Mar 1, 2024Biochemistry

Matrix stiffness regulates Notch signaling activity in endothelial cells

M. Kretschmer, R. Mamistvalov, D. Sprinzak, A. M. Vollmar, S. Zahler

This study shows that substrate stiffness inversely regulates Notch signaling activity in endothelial cells during angiogenesis.

bioRxiv · Apr 20, 2022Cell Biology

A nesprin-4/kinesin-1 cargo model for nuclear positioning in cochlear outer hair cells

S. Taiber, O. Gozlan, R. Cohen, L. R. Andrade, E. F. Gregory, D. A. Starr, Y. Moran, R. Hipp, M. W. Kelley, U. Manor, D. Sprinzak, K. B. Avraham

This study identifies a conserved 4-amino-acid motif in nesprin-4 that mediates its interaction with kinesin-1, essential for nuclear positioning in outer hair cells and hearing.

bioRxiv · Oct 10, 2021Cell Biology