SARS-CoV-2 escapes direct NK cell killing through Nsp1-mediated downregulation of ligands for NKG2D
M. J. Lee, M. W. Leong, A. Rustagi, A. Beck, L. Zeng, S. Holmes, L. S. Qi, C. A. Blish
This study shows SARS-CoV-2 evades NK cell killing by downregulating NKG2D ligands via Nsp1, reducing NK cell cytotoxicity against infected cells.
bioRxiv · Jun 20, 2022Immunology