Endogenous sterol synthesis is dispensable for Trypanosoma cruzi epimastigote growth but not stress tolerance
P. Dumoulin, J. Vollrath, M. Won, J. X. Wang, B. A. Burleigh
This study shows that CYP51 is not essential for T. cruzi epimastigote growth but is required for stress tolerance, as its disruption leads to sterol auxotrophy and sensitivity to elevated temperature.
bioRxiv · May 3, 2022Microbiology