Author

B. A. Burleigh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

J. Vollrath· 2 shared J. X. Wang· 2 shared M. M. Won· 2 shared P. C. Dumoulin· 2 shared A. Baublis· 1 shared C. C. Ellis· 1 shared I. C. Almeida· 1 shared I. L. Estevao· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersMicrobiology

J. Vollrath

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Author profile →

5 papers

Recent·Most cited

Proximity-dependent biotinylation and identification of flagellar proteins in Trypanosoma cruzi

M. M. Won, A. Baublis, B. A. Burleigh

This study identifies flagellar proteins in Trypanosoma cruzi using proximity-dependent biotinylation and mass spectrometry, revealing 218 and 99 candidates in two life stages.

bioRxiv · Feb 16, 2023 · PreprintMicrobiology

The intracellular amastigote of Trypanosoma cruzi maintains an actively beating flagellum

M. M. Won, T. Krüger, M. Engstler, B. A. Burleigh

This study shows that intracellular Trypanosoma cruzi amastigotes have a beating flagellum, challenging the previous belief that these forms are non-motile.

bioRxiv · Nov 23, 2022 · PreprintCell Biology

Fatty acid elongases 1-3 have distinct roles in mitochondrial function, growth and lipid homeostasis in Trypanosoma cruzi.

L. Pagura, P. C. Dumoulin, C. C. Ellis, I. L. Estevao, M. T. Mendes, I. C. Almeida, B. A. Burleigh

This study identifies distinct roles of ELO1, ELO2, and ELO3 in lipid homeostasis and mitochondrial function in T. cruzi.

bioRxiv · Nov 22, 2022 · PreprintMicrobiology

Endogenous sterol synthesis is dispensable for Trypanosoma cruzi epimastigote growth but not stress tolerance

P. Dumoulin, J. Vollrath, M. Won, J. X. Wang, B. A. Burleigh

This study shows that CYP51 is not essential for T. cruzi epimastigote growth but is required for stress tolerance, as its disruption leads to sterol auxotrophy and sensitivity to elevated temperature.

bioRxiv · May 3, 2022Microbiology

Glutamine metabolism modulates azole susceptibility in Trypanosoma cruzi amastigotes

P. C. Dumoulin, J. Vollrath, J. X. Wang, B. A. BURLEIGH

This study shows that glutamine metabolism affects azole susceptibility in Trypanosoma cruzi amastigotes by influencing sterol biosynthesis and metabolic intermediates.

bioRxiv · Jun 19, 2020Microbiology