T. Green

Germline variation contributes to false negatives in CRISPR-based experiments with varying burden across ancestries

The paper identifies ancestry-related biases in CRISPR experiments caused by germline variants, showing disproportionate effects in cell models from recent African descent.

Subjective assessment and taste strips testing of gustatory function, at home, and in the lab

The paper compares lab and home-based taste strips tests for gustatory function in healthy subjects, finding similar results between settings but no correlation between self-rated taste ability and test scores.

Single-dose intranasal administration of AdCOVID elicits systemic and mucosal immunity against SARS-CoV-2 in mice

This study shows that AdCOVID, an intranasal vaccine, induces both systemic and mucosal immunity against SARS-CoV-2 in mice.

Evaluation of Field Sampling Techniques for Environmental Microbial Exposure: Assessing Efficacy and Feasibility

The paper compares two microbial sampling techniques in schools, finding electrostatic cloths more effective than swabs for quantifying Staphylococcus burden.

Non-canonical open reading frames encode functional proteins essential for cancer cell survival

The paper identifies non-canonical open reading frames (ORFs) that encode functional proteins essential for cancer cell survival, with one example, GREP1, showing preferential essentiality in breast cancer.

Agreement between two large pan-cancer CRISPR-Cas9 gene dependency datasets

This study compares two large pan-cancer CRISPR-Cas9 screens, finding high concordance in gene dependencies despite differences in protocols and reagents.