Herbal medicine of Kursi Wufarikun Ziyabit inhibits mitochondrial ATP production to activate AMPK in hepatocytes in therapy of type 2 diabetes
M. Yasen, L. Jiang, M. Sharofova, X. Xin, Y. Nuraliev, J. Ye, H. A. Aisa
This study investigates how the herbal medicine Kursi Wufarikun Ziyabit inhibits mitochondrial ATP production, activates AMPK, and induces FGF21 expression in hepatocytes, suggesting a mechanism for its therapeutic effect in type 2 diabetes.
bioRxiv · Sep 28, 2020 · PreprintBiochemistry