Author

H. A. Aisa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Assay:structural biology· 1

Frequent Co-Authors

D. Shen· 1 shared D. Wei· 1 shared F. Zhou· 1 shared G. Tian· 1 shared G. Xiao· 1 shared H. E. Xu· 1 shared H. Jiang· 1 shared J. Liu· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBiophysics

D. Shen

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Structural basis for repurpose and design of nucleoside drugs for treating COVID-19

W. Yin, X. Luan, Z. Li, Y. Xie, Z. Zhou, J. Liu, M. Gao, X. Wang, F. Zhou, Q. Wang, Q. Wang, D. Shen, Y. Zhang, G. Tian, H. A. Aisa, , H. E. Xu

The paper reports cryo-EM structures of SARS-CoV-2 RdRp with nucleoside inhibitors, revealing their mechanism and guiding the design of more potent derivatives.

bioRxiv · Nov 1, 2020 · PreprintBiophysics

Herbal medicine of Kursi Wufarikun Ziyabit inhibits mitochondrial ATP production to activate AMPK in hepatocytes in therapy of type 2 diabetes

M. Yasen, L. Jiang, M. Sharofova, X. Xin, Y. Nuraliev, J. Ye, H. A. Aisa

This study investigates how the herbal medicine Kursi Wufarikun Ziyabit inhibits mitochondrial ATP production, activates AMPK, and induces FGF21 expression in hepatocytes, suggesting a mechanism for its therapeutic effect in type 2 diabetes.

bioRxiv · Sep 28, 2020 · PreprintBiochemistry