ZEB1 insufficiency causes corneal endothelial cell state transition and altered cellular processing
R. F. Frausto, D. D. Chung, P. M. Boere, V. S. Swamy, H. N. V. Duong, L. Kao, R. Azimov, W. Zhang, L. Carrigan, D. Wong, M. Morselli, M. Zakharevich, E. M. Hanser, A. C. Kassels, I. Kurtz, , A. J. Aldave
This study shows that ZEB1 insufficiency in corneal endothelial cells leads to a MET-like transition, altering cellular phenotype and transcriptomic profile in a model of PPCD.
bioRxiv · Feb 12, 2019Cell Biology