Cyclin B3-CDK1 couples translational de-repression to embryonic mitoses via OMA protein degradation in C. elegans.
David Bojorquez, Shabnam Moghareh, Maab Elsayed, Amrutha Kizhedathu, Gio Jison, Lee Bardwell, Pablo Lara-González
This study shows that cyclin B3-CDK1 promotes mRNA de-repression in C. elegans embryos by degrading OMA proteins, linking mitosis to early gene expression.
bioRxiv · Jul 23, 2026 · PreprintDevelopmental Biology