Shabnam Moghareh

The paper develops a tissue-targeted auxin-inducible degradation toolkit for C. elegans embryogenesis and shows that LET-502 degradation in the epidermis disrupts elongation, with unexpected roles in both early and late stages.

This study shows cyclin B3-CDK1/2 drives mitotic progression and fidelity in cancer cells, with overexpression accelerating mitosis and depletion disrupting it in multiple cancer models.

This study shows that cyclin B3-CDK1 promotes mRNA de-repression in C. elegans embryos by degrading OMA proteins, linking mitosis to early gene expression.