Cell BiologybioRxivPreprint
A functional map of phosphoprotein phosphatase regulation identifies an evolutionary conserved reductase for the catalytic metal ions
Bob Meeusen, Sara M. Ambjørn, Jiri Veis…·Jakob Nilsson
The paper identifies CYB5R4 as an evolutionarily conserved reductase that activates PP4 and PP6 by reducing their catalytic metal ions, essential for cell viability under oxidative stress.