Optimized photochemistry and enzymology enable efficient analysis of RNA structures and interactions in cells and virus infections
Minjie Zhang, Kongpan Li, Willem A. Velema, Jianhui Bai, Chengqing Yu, Ryan Van Damme, Wilson H. Lee, Maia L. Corpuz, Jian‐Fu Chen, Zhipeng Lu
The paper introduces PARIS2, a method for efficiently analyzing RNA structures and interactions in cells, revealing new insights into viral RNA conformations and translation mechanisms.
bioRxiv · Apr 30, 2020 · PreprintGenomics