Jian‐Fu Chen

PRMT1-SFPQ regulates intron retention to control matrix gene expression during craniofacial development

This study identifies PRMT1-SFPQ as a regulator of intron retention in craniofacial development, leading to reduced matrix gene expression through NMD.

Periosteal and periarticular compartments house lymphatic vessels in bone

This study identifies that lymphatic vessels in bone are confined to periosteal and periarticular compartments and absent from bone marrow.

Classification and clustering of RNA crosslink-ligation data reveal complex structures and homodimers

The paper introduces computational tools to analyze crosslink-ligation RNA data, revealing new RNA structures and homodimers.

Atp13a5 Marker Reveals Pericytes of The Central Nervous System in Mice

The paper identifies Atp13a5 as a specific marker for CNS pericytes in mice and develops a transgenic model to study their biology.

Microvascular Injury in Mild Traumatic Brain Injury Accelerates Alzheimer-like Pathogenesis in Mice

This study shows that microvascular injury from mild TBI accelerates Alzheimer-like pathology in mice, suggesting vascular repair could mitigate AD risk.

Optimized photochemistry and enzymology enable efficient analysis of RNA structures and interactions in cells and virus infections

The paper introduces PARIS2, a method for efficiently analyzing RNA structures and interactions in cells, revealing new insights into viral RNA conformations and translation mechanisms.