Inhibition of MRN activity by a telomere protein motif
Freddy Khayat, Elda Cannavò, Majedh Alshmery, William R. Foster, Charly Chahwan, Martino Maddalena, Christopher D. Smith, Antony W. Oliver, Adam T. Watson, Antony M. Carr, Petr Ćejka, Alessandro Bianchi
The paper shows that the MIN motif in Rif2 inhibits MRN complex activity at telomeres, preventing DDR activation and NHEJ in yeast.
Nature Communications · Jun 22, 2021Peer-reviewedGenetics