Engineering a Biosynthetic Pathway for the Production of (+)-Brevianamides A and B in Escherichia coli
Casandra P Sandoval Hurtado, Samantha P. Kelly, Vikram V. Shende, Makayla Perez, Brian J. Curtis, Sean A. Newmister, Kaleb Ott, Filipa M. Pereira, David H. Sherman
The paper designs an engineered biosynthetic pathway in E. coli to produce (+)-brevianamides A and B, achieving a 46% yield with a 92:8 diastereomeric ratio.
bioRxiv · Dec 10, 2024 · PreprintSynthetic Biology