Author

Kaleb Ott

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Organism:E. coli· 1 Organism:human· 1

Frequent Co-Authors

Brian J. CurtisiD· 1 shared Carole A. ParentiD· 1 shared Casandra P Sandoval Hurtado· 1 shared David H. ShermaniD· 1 shared Erez CoheniD· 1 shared Filipa M. PereiraiD· 1 shared Joseph SerrenhoiD· 1 shared Makayla Perez· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperSynthetic Biology

Brian J. CurtisORCID

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2 papers

Recent·Most cited

TGFβ1-TNFα regulated secretion of neutrophil chemokines is independent of epithelial-mesenchymal transitions in breast tumor cells

Shuvasree SenGupta, Erez Cohen, Joseph Serrenho, Kaleb Ott, Pierre A. Coulombe, Carole A. Parent

This study shows that TGFβ1-TNFα-induced neutrophil chemokine secretion in breast tumor cells occurs independently of EMT.

Molecular Biology of the Cell · Aug 20, 2025Peer-reviewedCancer Biology

Engineering a Biosynthetic Pathway for the Production of (+)-Brevianamides A and B in Escherichia coli

Casandra P Sandoval Hurtado, Samantha P. Kelly, Vikram V. Shende, Makayla Perez, Brian J. Curtis, Sean A. Newmister, Kaleb Ott, Filipa M. Pereira, David H. Sherman

The paper designs an engineered biosynthetic pathway in E. coli to produce (+)-brevianamides A and B, achieving a 46% yield with a 92:8 diastereomeric ratio.

bioRxiv · Dec 10, 2024 · PreprintSynthetic Biology