Author

Malek W. Elsayyid

University of Delaware

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:C. elegans· 3 Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Jessica E. TanisiD· 3 shared Nahin Siara Prova· 2 shared Alexis E. Semmel· 1 shared Krisha D. Parekh· 1 shared Tao Ke· 1 shared Yanbao YuiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

Jessica E. TanisORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cell BiologybioRxivPreprintNov 4, 2025

Superoxide dismutase impacts extracellular vesicle biogenesis and uptake

Nahin Siara Prova, Malek W. Elsayyid, Jessica E. Tanis

This study shows that SOD-1 affects EV shedding from cilia, cargo enrichment, and glial uptake in C. elegans, highlighting redox balance's role in EV biogenesis and neuron communication.

DOI 10.1101/2025.11.04.686557

C. elegansspatial transcriptomics

𝕏 PostBluesky

Cell BiologyJournal of Cell SciencePeer-reviewedOct 9, 2025

Phosphatidylinositol (4,5)-bisphosphate Impacts Extracellular Vesicle Shedding from C. elegans Ciliated Sensory Neurons

Malek W. Elsayyid, Alexis E. Semmel, Krisha D. Parekh…·Jessica E. Tanis

This study investigates how phosphatidylinositol (4,5)-bisphosphate (PI(4,5)P2) affects extracellular vesicle (EV) shedding from C. elegans ciliated sensory neurons, revealing differential impacts on EV subpopulations.

7 citations

C. elegansproteomics

𝕏 PostBluesky

BiochemistryAnalytical ChemistryPeer-reviewedApr 21, 2025

In-cell processing enables rapid and in-depth proteome analysis of low-input Caenorhabditis elegans

Malek W. Elsayyid, Jessica E. Tanis, Yanbao Yu

This paper introduces an in-cell proteomics method for C. elegans that enables high-throughput proteome analysis with minimal sample input and identifies proteomic changes in sod-1 mutants.

10 citations

C. elegansproteomics

𝕏 PostBluesky