Jessica E. Tanis

Superoxide dismutase impacts extracellular vesicle biogenesis and uptake

This study shows that SOD-1 affects EV shedding from cilia, cargo enrichment, and glial uptake in C. elegans, highlighting redox balance's role in EV biogenesis and neuron communication.

Phosphatidylinositol (4,5)-bisphosphate Impacts Extracellular Vesicle Shedding from C. elegans Ciliated Sensory Neurons

This study investigates how phosphatidylinositol (4,5)-bisphosphate (PI(4,5)P2) affects extracellular vesicle (EV) shedding from C. elegans ciliated sensory neurons, revealing differential impacts on EV subpopulations.

C. elegans CED-1 acts in neurons to modulate ciliary protein abundance and extracellular vesicle shedding

This study shows CED-1 in C. elegans neurons regulates extracellular vesicle shedding and ciliary protein abundance during mating.

In-cell processing enables rapid and in-depth proteome analysis of low-input Caenorhabditis elegans

This paper introduces an in-cell proteomics method for C. elegans that enables high-throughput proteome analysis with minimal sample input and identifies proteomic changes in sod-1 mutants.

A C. elegans genome-wide RNAi screen for altered levamisole sensitivity identifies genes required for muscle function

The paper identifies genes affecting levamisole sensitivity in C. elegans by RNAi screening, revealing roles in muscle function and metabolic processes.

A rapid, super-selective method for detection of single nucleotide variants in C. elegans

The paper introduces a method for detecting single nucleotide variants in C. elegans using optimized SuperSelective primers for endpoint PCR.

Activity of the C. elegans egg-laying behavior circuit is controlledby competing activation and feedback inhibition

The paper investigates the neural circuit controlling C. elegans egg-laying behavior, identifying signals that switch between active and inactive states.