Author

Manabu Iwadate

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Huaitian LiuiD· 1 shared Jerrold Michael WardiD· 1 shared Masaaki Miyakoshi· 1 shared Shigetoshi YokoyamaiD· 1 shared Shioko KimuraiD· 1 shared Shogo EhataiD· 1 shared Suguru HayaseiD· 1 shared Tsubasa Murata· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Huaitian LiuORCID

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1 paper

Recent·Most cited

Loss of NKX2-1 predisposes thyroid to neoplasm development through regulation of oxidative stress

Yo-Taro Shirai, Jerrold Michael Ward, Yoshinori Takizawa, Huaitian Liu, Masaaki Miyakoshi, Manabu Iwadate, Tsubasa Murata, Suguru Hayase, Shigetoshi Yokoyama, Shogo Ehata, Shioko Kimura

The paper shows that loss of NKX2-1 increases thyroid cancer risk by promoting oxidative stress through ROS production and DNA damage in mice exposed to radiation and iodine deficiency.

bioRxiv · Aug 27, 2026 · PreprintCancer Biology