Author

Shigetoshi Yokoyama

National Institutes of HealthORCID 0000-0003-4175-0548Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Hiroe Ueno-Kudoh· 1 shared Hiroshi AsaharaiD· 1 shared Huaitian LiuiD· 1 shared Jerrold Michael WardiD· 1 shared Keiichi AkitaiD· 1 shared Kensuke Kataoka· 1 shared Manabu Iwadate· 1 shared Masaaki Miyakoshi· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperDevelopmental Biology

Hiroe Ueno-Kudoh

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 27, 2026

Loss of NKX2-1 predisposes thyroid to neoplasm development through regulation of oxidative stress

Yo-Taro Shirai, Jerrold Michael Ward, Yoshinori Takizawa…·Shioko Kimura

The paper shows that loss of NKX2-1 increases thyroid cancer risk by promoting oxidative stress through ROS production and DNA damage in mice exposed to radiation and iodine deficiency.

DOI 10.64898/2026.08.26.746581

mousebulk RNA-seq

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Developmental BiologyeLifePeer-reviewedMay 29, 2020

Lin28a/let-7 Pathway Modulates the Hox Code via Polycomb Regulation during Axial Patterning in Vertebrates

Tempei Sato, Kensuke Kataoka, Yoshiaki Ito…·Hiroshi Asahara

This study shows the Lin28a/let-7 pathway regulates Hox gene expression during axial patterning by modulating Polycomb complex occupancy in vertebrates.

17 citations

mousestatistical model

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