Jerrold Michael Ward

Loss of NKX2-1 predisposes thyroid to neoplasm development through regulation of oxidative stress

The paper shows that loss of NKX2-1 increases thyroid cancer risk by promoting oxidative stress through ROS production and DNA damage in mice exposed to radiation and iodine deficiency.

SL/Kh Pre-B Lymphomas Originate in the Thymus and are a Model for Primary Mediastinal (Thymic) Large B-Cell Lymphoma

This paper identifies thymus-origin pre-B lymphomas in SL/Kh mice and links them to human mediastinal large B-cell lymphoma through Notch1 signaling and retroviral mutagenesis.

Characterization of Collaborative Cross mouse founder strain CAST/EiJ as a novel model for lethal COVID-19

The paper characterizes the CAST/EiJ mouse strain as a model for severe COVID-19 by showing it develops high viral burdens, severe lung pathology, and cytokine dysregulation leading to mortality.