Basolateral amygdala circuits supporting negative emotional bias in a mouse model for depression
Mathilde Bigot, Claire-Hélène De Badts, Axel Benchetrit, Éléonore Vicq, Carine Moigneu, Manon Meyrel, Sébastien Wagner, Josselin Houenou, Pierre‐Marie Lledo, Chantal Henry, Mariana Alonso
The paper shows that depressive-like states in mice exhibit negative emotional bias, linked to altered basolateral amygdala (BLA) circuits and mitigated by antidepressants or chemogenetic interventions.
bioRxiv · Jan 23, 2023 · PreprintNeuroscience