Axel Benchetrit

The paper develops a multiplex CRISPR-Cas9 gRNA toolkit to generate fully unpigmented zebrafish larvae with minimal mortality, enabling improved imaging without chemical inhibitors.

This study identifies PDGFRβ signaling as critical for meningeal cell recruitment and tissue remodeling during zebrafish CNS injury repair.

The paper identifies SIRanc, a human homolog of bacterial antiphage SIR2 proteins, and shows it mediates innate immunity via the TLR pathway by degrading NAD+.

The paper shows that depressive-like states in mice exhibit negative emotional bias, linked to altered basolateral amygdala (BLA) circuits and mitigated by antidepressants or chemogenetic interventions.