Mathilde Bigot

The paper shows that depressive-like states in mice exhibit negative emotional bias, linked to altered basolateral amygdala (BLA) circuits and mitigated by antidepressants or chemogenetic interventions.

The paper shows that plasticity of inhibitory synapses onto layer 5 pyramidal neurons modulates excitation-inhibition ratios, neuronal gain, and information transfer across cortical layers.

The paper shows that stress alters gut microbiota, which can induce depression and reduce neurogenesis, but this effect is blocked by vagus nerve disruption.