Carine Moigneu

This study investigates the role of vagal subcircuits in sepsis-induced brain dysfunction using rodent models and manipulates vagus nerve activity to assess its impact on inflammation and behaviour.

The paper shows that depressive-like states in mice exhibit negative emotional bias, linked to altered basolateral amygdala (BLA) circuits and mitigated by antidepressants or chemogenetic interventions.

The paper shows that stress alters gut microbiota, which can induce depression and reduce neurogenesis, but this effect is blocked by vagus nerve disruption.