Silica-mediated exacerbation of inflammatory arthritis: A novel murine model
Lisa Janssen, Caroline de Ocampo, Dwight H. Kono, Steven Ronsmans, Manosij Ghosh, Peter Hoet, K. Michael Pollard, Jessica Mayeux
This paper develops a novel murine model of silica-induced inflammatory arthritis by exposing arthritis-prone mice to crystalline silica, showing it induces arthritis and autoimmunity while DR4-Tg mice are resistant.
Particle and Fibre Toxicology · Feb 9, 2026Peer-reviewedImmunology