Lisa Janssen

The paper shows that B cell-derived IgG in DRG meninges forms tertiary lymphoid structures (TLSs) that drive neuropathic pain after peripheral nerve injury, and disrupting TLSs prevents pain.

This paper develops a novel murine model of silica-induced inflammatory arthritis by exposing arthritis-prone mice to crystalline silica, showing it induces arthritis and autoimmunity while DR4-Tg mice are resistant.

This study shows that silica exposure causes autoimmune diseases in mice with pre-existing subclinical autoimmunity, leading to more severe outcomes like arthritis and nephritis.

This study shows that aging increases spontaneous autoimmunity but reduces xenobiotic-induced autoimmunity in mice, with some older mice still showing a diminished response.