Excessive immune responses in preterm placental villi compromise trophoblast health
Tyler Rice, Yi Cao, Leon Bichmann, Mar Ivar Ribes, Taylor Snisky, Serrena Singh, Weihong Gu, Dean Yimlamai, Jonathan S. D. Radda, Siyuan S. Wang, Raffaella Morotti, John S. Tsang, Christina Megli, Liza Konnikova
The paper examines immune cell composition and function in placental villi, finding that excessive T cells and cytokines in preterm cases impair trophoblast health.
bioRxiv · Sep 20, 2025 · PreprintImmunology